2026
Impact of spleen volume and volume change in non-Hodgkin lymphoma treated with chimeric antigen receptor t-cell therapy
Quell, C., Kunz, W. G., Blumenberg, V. et al. (2026) Cancer Treatment and Research Communications
DOI: 10.1016/j.ctarc.2025.101080
This study demonstrates that an early decrease in spleen volume between baseline and a 30-day follow-up is a significant predictor of improved progression-free survival (PFS) and overall survival (OS) in patients with relapsed or refractory non-Hodgkin lymphoma (NHL) - including LBCL, MCL, and FL - treated with CD19-specific CAR T-cell therapy. Researchers utilized the Lugano criteria for response assessment and identified spleen volume change as a potential novel dynamic biomarker.
mint Lesion was used to perform the imaging analyses, specifically for the 3D segmentation of the spleen and the evaluation of up to six target lesions, and to categorize treatment response in line with the Lugano criteria.
Circulating tumor DNA is prognostic of patient outcome and enables therapy monitoring in metastatic uveal melanoma
E Ramelyte, E., Kött, J., Lawless, A. R. et al. (2026) Clinical Cancer
DOI: 10.1158/1078-0432.CCR-25-2274
In this study, researchers demonstrated that the absence of detectable circulating tumor DNA (ctDNA) at baseline is a strong predictor of improved survival for patients with metastatic uveal melanoma. The quantitative level of ctDNA also proved critical, as a mutant allele fraction (MAF) greater than 5% at any point correlated with significantly poorer outcomes compared to lower levels. Ultimately, the findings suggest that both the presence of ctDNA before treatment and its persistence within the first three months of therapy serve as powerful noninvasive markers for monitoring disease progression.
Baseline CT imaging parameters predicting overall and progression-free survival for patients with pulmonary metastases from soft tissue and bone sarcoma.
Klambauer, K., Gold, L., Klinge, L. et al. (2026) Eur Radiol
In this study, researchers found that the number of pulmonary lesions (specifically ≥ 5) on baseline CT scans independently predicted shorter overall survival for patients with soft tissue and bone sarcoma. Conversely, measurements of tumor burden showed no significant prognostic value for survival or disease progression. Ultimately, while lesion count serves as a predictor for overall survival, no specific imaging parameter was found to independently predict progression-free survival.
[18F]SiTATE PET for PRRT selection and monitoring metastatic tumors of the adrenal medulla and extra-adrenal paraganglia.
Siegmund, S.C., Holzgreve, A., Schöll, M. et al. (2026) Eur J Nucl Med Mol Imaging
DOI: 10.1007/s00259-025-07550-2
This study evaluates the feasibility of using [18F]SiTATE PET/CT to determine eligibility and monitor treatment response in patients with metastatic pheochromocytoma and paraganglioma (PPGL) undergoing peptide receptor radionuclide therapy (PRRT). Researchers confirmed PRRT eligibility based on high somatostatin receptor expression using the Krenning score, finding that while all patients achieved stable disease per RECIST 1.1, follow-up assessments showed heterogeneous results between metabolic, morphologic and biochemical measures.
mint Lesion was utilized to evaluate diagnostic CT scans according to RECIST 1.1 to provide a morphologic assessment of treatment response.
Performance analysis of liver segmentation using nn-UNet TotalSegmentator: Focus on atypical livers, pathologies, and variants
Kleiß, J.-M., Arndt, S., Sommerfeld, L. et al. (2026) European Journal of Radiology
DOI: 10.1016/j.ejrad.2026.112674
This study evaluates the accuracy of the nn-UNet TotalSegmentator AI model for automatic liver segmentation in abdominal CT scans, specifically comparing healthy livers against atypical cases involving pathologies such as polycystic liver disease (PLD), cirrhosis with ascites, metastases, and hepatomegaly. While the model performed excellently on healthy livers with high Dice scores, clinical evaluations revealed significant limitations in complex pathological cases, particularly PLD.
mint Lesion was utilized as the data management platform to pseudonymize and transfer imaging data from the local PACS to the research infrastructure. It also functioned as a structured reporting platform that served as the primary stage in the workflow before data was moved to specialized tools for deep learning analysis.
A comprehensive quantitative and qualitative assessment of TGSE-BLADE DWI in postoperative imaging following intracranial tumor resection,
Ruff, C., Hauser, T.-K., Bombach, P. et al. (2026) European Journal of Radiology
DOI: 10.1016/j.ejrad.2026.112659
This study compares the performance of TGSE-BLADE DWI and RESOLVE DWI for identifying perioperative ischemic changes in patients following the resection of intracranial tumors, such as glioblastoma, pilocytic astrocytoma, and metastases. The findings demonstrate that TGSE-BLADE DWI significantly reduces susceptibility artifacts and geometric distortions caused by intracranial air, resulting in superior image quality and higher diagnostic confidence compared to RESOLVE DWI.
mint Lesion was employed by neuroradiologists to perform bidimensional measurements of the resection defect. These measurements allowed the researchers to quantitatively assess the extent of geometric distortion across different MRI sequences compared to T1-weighted reference images.
Association of layer-specific knee cartilage T2-relaxation measurements with age, sex and cartilage morphology at 1.5-T MRI
Aschauer, K., Weber, MA., Bülow, R. et al. (2026) European Radiology
DOI: link.springer.com/article/10.1007/s00330-025-11806-8
This study established 1.5-T MRI T2-relaxation reference values for knee cartilage across 929 volunteers, demonstrating that T2-values are significantly higher in superficial layers and increase with age and female sex. The research also found that pathological cartilage morphology, defined by the modified Noyes Score, is associated with elevated T2-values compared to structurally normal cartilage.
mint Lesion was utilized for cartilage T2-mapping analysis and morphological knee evaluation, including the assessment of the modified Noyes Grading. It also facilitated manual cartilage segmentation by readers to delineate regions of interest across the knee joint.
2025
Predictive value of maximum tumor dissemination (Dmax) in lymphoma patients treated with CD19-specific CAR T-Cells.
Winkelmann, M., Achhammer, P., Blumenberg, V. et al. (2025) Cancer Imaging
DOI: 10.1186/s40644-025-00959-w
This study evaluates the prognostic value of maximum tumor dissemination (Dmax) in patients with relapsed or refractory large B-cell lymphoma (LBCL) and mantle-cell lymphoma (MCL) treated with CD19-specific CAR T-cell therapy. The research found that high baseline Dmax is a significant predictor of shorter progression-free survival (PFS) when assessed via Lugano criteria, though it showed no significant association with overall survival. The authors suggest that while Dmax is a useful imaging biomarker, future studies should explore its combination with radiomics and artificial intelligence to further improve risk stratification.
mint Lesion was the dedicated trial reporting software used to perform all structured imaging analyses for Lugano assessment at baseline and follow-up timepoints for patients with relapsed or refractory large B-cell lymphoma (LBCL) and mantle-cell lymphoma (MCL).
Phase Ia/b Multicenter Study of BPM31510IV Targeting Mitochondrial Metabolism/Warburg Effect as Monotherapy and Combination Chemotherapy in Solid Tumor Patients
Vivek Subbiah, V., Yu, P. P., Sarangarajan, R. et al. (2025) Cancer Research Communications
DOI: 10.1158/2767-9764.CRC-25-0507
This phase Ia/Ib multicenter study evaluated the safety, pharmacokinetics, and preliminary antitumor activity of BPM31510IV (a lipid nanodispersion of oxidized Coenzyme Q10) as monotherapy or in combination with chemotherapy in patients with advanced solid tumors. The trial found the treatment to be well-tolerated with evidence of a metabolic shift from glycolysis to oxidative phosphorylation.
mint Lesion was used for tumor response assessment in line with RECIST 1.1 and to automatically generate quantitative metabolic data from 18FDG-PET/CT scans, including standardized uptake values (SUVmax, SUVpeak, SUVmean), metabolic tumor volume (MTV), and total glycemic index (TGI). These metrics provided a whole-body assessment of metabolic tumor burden to measure longitudinal changes in response to treatment.
Pembrolizumab and Olaparib (POLAR) Maintenance Therapy in Metastatic Pancreatic Cancer With or Without Homologous Repair Deficiency: A Biomarker Selected Phase II Trial
Park, W., O'Connor, C.. Chou, J. et al. (2025) Preprint
DOI: 10.21203/rs.3.rs-7334701/v1
This phase II trial (POLAR) evaluated the efficacy of maintenance pembrolizumab and olaparib in patients with metastatic pancreatic cancer (mPC) who achieved disease control on platinum-based chemotherapy. While the primary endpoint was not met in the core homologous recombination deficiency (HRD) cohort, the combination demonstrated clinical activity with a 6-month progression-free survival rate of 64% and an overall response rate of 35%.
mint Lesion was utilized for the independent radiology review to conduct standardized treatment response assessments according to RECIST 1.1 guidelines. The software ensured reproducible data capture for the trial’s primary and secondary efficacy endpoints.
Peptide Receptor Radionuclide Therapy with Lu-177-DOTATATE and Monitoring with Somatostatin Receptor PET/CT in Patients with Advanced Differentiated Thyroid Carcinoma
Kunte, S. C., Wenter, V. U., Holzgreve, A. et al. (2025) Mol Imaging Biol
DOI: 10.1007/s11307-025-02053-w
This study evaluates the efficacy and safety of Lu-177-DOTATATE peptide receptor radionuclide therapy (PRRT) in seven patients with advanced radioiodine-refractory differentiated thyroid carcinoma (DTC). The results demonstrate that PRRT is a beneficial and well-tolerated treatment option, achieving renewed tumor control even in a "rechallenge" scenario where treatment was reinitiated after an interruption of over one year. No major side effects (CTCAE Grade 3–5) were observed, indicating its potential for patients with limited alternative therapies.
mint Lesion was used for the standardized evaluation of CT datasets to define and measure target/non-target lesions according to RECIST 1.1.
Artificial Intelligence-Assisted Biparametric MRI for Detecting Prostate Cancer—A Comparative Multireader Multicase Accuracy Study
Nißler, D., Reimers-Kipping, S., Ingwersen, M. et al. (2025) J. Clin. Med.
DOI: 10.3390/jcm14176111
This retrospective, multireader multicase study evaluated the diagnostic accuracy of artificial intelligence-assisted biparametric MRI (AI-bpMRI) compared to standard bpMRI and multiparametric MRI (mpMRI) for detecting prostate cancer (PCa). The study found that AI-bpMRI is non-inferior to mpMRI for detecting clinically significant prostate cancer (Gleason score ≥ 3+4) and superior to standard bpMRI for all PCa cases.
In this study, the Prostate.Carcinoma.ai AI algorithm was integrated into the mint Lesion platform to provide a standardized, computer-assisted reading environment for the PI-RADS 2.1 assessment. The software was used to automate the segmentation of the prostate gland and suspicious lesions, automatically calculate volumes and PSA density, and facilitate the generation of structured reports by mapping findings directly onto the prostate sector map.
Non-Hodgkin’s lymphoma classification using 3D radiomics machine learning models for precision imaging in oncology
Lisson, C. G., Götz, M., Wolf, D. et al. (2025) BMC Medical Imaging
DOI: 10.1186/s12880-025-02006-3
This study shows that 3D radiomics combined with a multiclass machine learning model (LightGBM) can non-invasively classify healthy lymph nodes and differentiate between major Non-Hodgkin lymphoma (NHL) subtypes—specifically DLBCL, FL, CLL, and MCL—using routine contrast-enhanced CT. The findings establish a high-accuracy "precision imaging" approach for subtype-level classification, which could streamline biopsy guidance and enhance therapeutic monitoring.
The researchers used mint Lesion to perform semi-automatic 3D segmentation of 1,762 individual lymph nodes and to conduct the subsequent texture analysis. The software was utilized to extract 78 radiomic features per lesion following the Image Biomarker Standardisation Initiative (IBSI) guidelines to ensure standardized quantification of tumor heterogeneity.
Predicting response and survival to firstline treatment with baseline [18F]FDG-PETCT in patients with small-cell lung cancer: an integrated diagnostic approach
Ventura, D. , Schindler, P., Kies, P. et al. (2025) Therapeutic Advances in Medical Oncology
DOI: 10.1177/17588359251379665
This study demonstrates that an integrated diagnostic approach combining CT-based radiomics, [¹⁸F]FDG-PET parameters (such as metabolic tumor volume), and clinical staging (UICC 8th edition) can accurately predict early disease progression and survival in patients with small-cell lung cancer (SCLC). Using machine learning and the LASSO algorithm, the researchers developed a multiparametric model that achieved a high predictive capacity (AUC 0.9) for treatment response and was significantly associated with both progression-free survival (PFS) and overall survival (OS).
mint Lesion was used for the standardized objective assessment of treatment response following RECIST 1.1 guidelines.
Machine learning-based radiomics for bladder cancer staging: evaluating the role of imaging timing in differentiating T2 from T3 disease
Lisson, C. G., Gallee, L, Müller, K et al. (2025) Front. Oncol.
DOI: 10.3389/fonc.2025.1591742
This study evaluates the use of CT-based machine learning radiomics to preoperatively differentiate between organ-confined (T2) and extravesical (T3) muscle-invasive bladder cancer. The researchers found that integrating clinical biomarkers and optimizing the timing of imaging relative to transurethral resection (TURB) significantly improved the model's predictive performance.
mint Lesion was used to perform semi-automated, three-dimensional (3D) tumor segmentation on contrast-enhanced CT scans to extract full-volume radiomic features. It provided the platform for manual slice-by-slice refinement of tumor boundaries by experienced radiologists to ensure high-quality data for the machine learning algorithms.
Enhancing LI-RADS Through Semi-Automated Quantification of HCC Lesions
Jöbstl, A., Tierno, P. M., Gerstner, A.-K. et al. (2025) J. Pers. Med.
DOI: 10.3390/jpm15090400
This publication evaluates a semi-automated method for quantifying imaging features of Hepatocellular Carcinoma (HCC) to enhance the reliability of the LI-RADS (Liver Imaging Reporting and Data System) classification. The study demonstrates that arithmetic assessment of key features, such as Arterial-Phase Hyperenhancement (APHE) and non-peripheral washout, provides high agreement with traditional visual assessment and can help resolve ambiguous cases.
mint Lesion was used for semi-automatic 3D segmentation of liver lesions and background liver to extract volumetric and density data (Hounsfield Units). It facilitated structured reporting by automatically calculating LI-RADS classifications based on extracted values and providing a text module for easy clinical integration.
Glioblastoma Multiforme Tumor Volume and Persistence of Chimeric Antigen Receptor T Cells Following Neurosurgical Debulking (P12-6.014)
Veerappan, D. and Thomas, R. (2025) Neurology
DOI: 10.1212/WNL.0000000000208956
This study examines the relationship between post-surgical tumor volume and the persistence of B7-H3 targeted CAR-T cells in patients with recurrent glioblastoma multiforme (GBM). The results demonstrated that CAR-T cell persistence was higher in patients with larger post-surgical tumor volumes, suggesting that this therapy may be a promising regimen for first-recurrence GBM.
mint Lesion was used to generate tumor response assessment reports. These reports provided critical volumetric measurements of the tumor lesions, specifically categorizing them into target enhancing, non-target enhancing, and non-target non-enhancing lesions.
Artificial intelligence for TNM staging in NSCLC: a critical appraisal of segmentation utility in [1⁸F]FDG PET/CT
Heimer, M. M., Dexl, J., Ta, J. et. al. (2025) European Journal of Nuclear Medicine and Molecular Imaging
DOI: 10.1007/s00259-025-07677-2
This study evaluates the clinical utility of a high-performing AI segmentation model for automated TNM staging in 306 treatment-naïve patients with non-small cell lung cancer (NSCLC) using [18F]FDG PET/CT. While the model demonstrated high lesion detection sensitivity, it achieved only 67.6% concordance with expert-derived UICC staging (9th edition), primarily due to frequent upstaging caused by false-positive predictions.
To establish the ground truth for the study, two hybrid imaging experts used mint Lesion to review all cases. All lesions were annotated and staged according to the 9th edition of the TNM classification system.
Modeling the involution of microwave liver ablation zones
Weston, W. B. N., White, O. A., Callister, R. et al. (2025) International Journal of Hyperthermia
DOI: 10.1080/02656736.2025.2525422
This retrospective study uses mathematical modeling to characterize the volumetric involution of microwave liver ablation zones in primary and metastatic tumors, such as colorectal liver metastases. The research demonstrates that this involution is best described by mono-exponential decay, with zones typically stabilizing at approximately one-third of their baseline volume within one year. Significant predictors of these dynamics include initial tumor diameter, initial ablation zone volume, and the tumor-to-ablation zone (T:AZ) volume ratio.
Researchers utilized mint Lesion to perform longitudinal semi-automatic segmentations of the ablation zones using the "interpolated VOI" tool, which employs a boundary-based interpolation algorithm. The software enabled the precise calculation of three-dimensional volumes by summing segmented voxels rather than assuming an ellipsoid or other geometric model.
Tumor grade-titude: XGBoost radiomics paves the way for RCC classification
Ellmann, S., von Rohr, F., Komina, S. et al. (2025) European Journal of Radiology
DOI: 10.1016/j.ejrad.2025.112146
This study developed an XGBoost machine learning model to non-invasively differentiate grade 4 renal cell carcinoma (RCC) from lower-grade tumors using radiomic features extracted from pre-treatment CT images. The model, which achieved a high AUC of 0.92 in the testing set, utilized the ISUP-WHO 2016 grading system as a reference standard and adhered to CLEAR and METRICS reporting guidelines.
Researchers utilized mint Lesion for image assessment and segmentation, defining a region of interest (ROI) at the largest axial diameter of the tumor. The software extracted 72 texture parameters in accordance with the Image Biomarker Standardisation Initiative (IBSI) to ensure international standardization and reproducibility.
CT-Defined Pectoralis Muscle Density Predicts 30-Day Mortality in Hospitalized Patients with COVID-19: A Nationwide Multicenter Study
Bucher, A. M., Behrend, J., Ehrengut, C. et al. (2025) Academic Radiology
DOI: 10.1016/j.acra.2024.11.054
This multicenter study within the RACOON network found that low pectoralis muscle density (LPMD) is a strong independent predictor of 30-day mortality in male patients and individuals under 60 hospitalized with COVID-19. While muscle quality was predictive, pectoralis muscle area did not predict mortality, and no significant associations were found for female patients or those over age 60. Assessment of patients also included a visual lung damage CT score to classify the extent of ground glass opacities and consolidations.
mint Lesion was utilized as the dedicated reporting and viewing software for radiologists to manually perform measurements of the pectoralis major and minor muscles. Specifically, it was used to draw polygonal regions of interest (ROI) on axial CT images to calculate pectoralis muscle area and density.
Radiomics-based differentiation of upper urinary tract urothelial and renal cell carcinoma in preoperative computed tomography datasets
Marcon, J., Weinhold, P., Rzany, M. et al. (2025) BMC Medical Imaging
DOI: 10.1186/s12880-025-01727-9
This study investigates a machine learning-based radiomics algorithm to non-invasively differentiate upper urinary tract urothelial carcinoma (UTUC) from renal cell carcinoma (RCC) using preoperative venous-phase CT datasets. Utilizing a LASSO regression model, the researchers analyzed 59 standardized radiomic features to achieve high diagnostic accuracy in distinguishing these tumor entities and identifying high-grade versus low-grade UTUC.
mint Lesion was utilized to perform manual tumor segmentation in the axial plane according to International Image Biomarker Standardization Initiative (IBSI) standards. Additionally, the software's algorithm was used to extract 59 radiomic features, encompassing first-order statistics and second-order texture descriptors, from the entire delineated tumor volume.
How I do it - KI-Support in der Prostata-MRT-Befundung [German]
Bayraktaroglu, H., Cyran, C. C., Kazmierczak, P. M. (2025) Radiologie up2date
DOI: 10.1055/a-2452-6978
This publication discusses the integration of AI-based systems into the reporting of multiparametric MRI (mpMRI) for prostate cancer to enhance diagnostic accuracy and workflow efficiency. It highlights the importance of standardized assessment guidelines, including PI-RADS version 2.1 and the S3-Guideline Prostate Cancer, to ensure high-quality and reproducible reporting.
mint Lesion was utilized as a software for generating structured reports, serving as the platform where AI-identified lesions are pre-segmented within T2-weighted sequences for the radiologist to review.
Impact of Concomitant Hormone Therapy on the Diagnostic Performance of 18F-Piflufolastat PET/CT in Prostate Cancer Patients: A Sub-Group Analysis of OSPREY Cohort B
Saperstein, L., Rowe, S. P., Gorin, M. A. et al. (2025) The Prostate
DOI: 10.1002/pros.24909
This sub-group analysis of OSPREY cohort B patients with recurrent or metastatic prostate cancer found that the diagnostic performance of 18F-piflufolastat PET/CT was unaffected by concomitant hormone therapy (HT) or castration status. The study demonstrated high median sensitivity (95.3%–96.4%) and similar positive predictive values across patient groups, regardless of whether they were receiving HT.
mint Lesion was used by independent readers to perform SUV measurements (SUVmax and SUVpeak) for identified lesions in various locations, such as bone, lymph nodes, and soft tissue. Readers utilized the software to place a volume of interest (VOI) on each lesion to determine the maximum and peak standardized uptake values.
Comparison of Gadoxetic Acid-Enhanced Liver Magnetic Resonance Imaging and Contrast-Enhanced Computed Tomography for the Noninvasive Diagnosis of Hepatocellular Carcinoma
Yoon, J. H., Chang, W., Kim, Y. K. et al. (2025) Liver Cancer
DOI: 10.1159/000545965
This retrospective multicenter study compared the diagnostic performance of contrast-enhanced CT and gadoxetic acid-enhanced MRI for diagnosing hepatocellular carcinoma (HCC) according to LI-RADS, APASL, and KLCA-NCC guidelines. The findings revealed that while MRI offered higher sensitivity under APASL and KLCA-NCC criteria, CT was more sensitive under LI-RADS due to the specific timing requirements for washout.
The study utilized mint Lesion to develop a review system and templates for structured image analysis. Radiologists used this platform to complete 46 questionnaires for assessing MRI features and 31 questionnaires for CT imaging features, specifically targeting major and ancillary features of focal liver lesions. As these questionnaires were completed, mint Lesion automatically assigned diagnostic classifications for each lesion based on LI-RADS, KLCA-NCC, and APASL guidelines. While the diagnostic results were automated, reviewers had the option for manual interaction, as they were permitted to manually adjust LI-RADS categories in specific cases where tie-breaking rules applied.
Real-world federated learning in radiology: hurdles to overcome and benefits to gain.
Bujotzek, M. R., Akuenal, U., Denner, S. et al. (2025) Journal of the American Medical Informatics Association
DOI: 10.1093/jamia/ocae259
This study establishes a real-world federated learning (FL) infrastructure within the German Radiological Cooperative Network (RACOON) to train deep learning segmentation models for lung pathologies, specifically consolidation, ground-glass opacity, and pleural effusion, on CT scans. The authors provide a comprehensive guide for overcoming practical and legal hurdles in radiology FL and demonstrate through benchmarking that collaborative FL approaches outperform local training and ensembling in both personalization and generalization scenarios.
Each participating hospital is equipped with a server hosting mint Lesion to facilitate structured radiological reporting. It serves as a key component of the initiative's clinical IT ecosystem alongside other tools used for imaging data annotation and processing.
The prognostic relevance of pleural effusion in patients with COVID-19 - A German multicenter study.
Bucher, A. M., Dietz, J., Ehrengut, C. et al. (2025) Clinical Imaging
DOI: 10.1016/j.clinimag.2024.110303
This German multicenter study, conducted within the RACOON project, identifies the presence of pleural effusion (PE) as a significant independent predictor of increased 30-day mortality, ICU admission, and the need for mechanical ventilation in COVID-19 patients. Utilizing a visual lung damage CT scoring system to assess disease severity, the researchers determined that the mere detection of PE on CT scans is a critical prognostic marker, regardless of the effusion's volume or density.
Radiologists used mint Lesion as a dedicated reporting and viewing software to manually measure the presence, width, and density of pleural effusions. The software supported a standardized measurement scheme where readers, blinded to clinical outcomes, performed calculations and placed regions of interest.
Replication study of PD-L1 status prediction in NSCLC using PET/CT radiomics.
Stueber, A. T., Heimer, M. M., Ta, J. et al. (2025) European Journal of Radiology
DOI: 10.1016/j.ejrad.2024.111825.
This study attempted to replicate a previously successful machine learning model that uses [18F]FDG PET/CT radiomics to predict PD-L1 expression in non-small cell lung cancer patients. While the original results were not mirrored in this cohort, the findings highlight the critical importance of rigorous validation and the ongoing challenges of standardizing radiomics for clinical use.
MRI and CT radiomics for the diagnosis of acute pancreatitis.
Tartari, C., Porões, F., Schmidt, S. et al. (2025) European Journal of Radiology Open
DOI: 10.1016/j.ejro.2025.100636
This prospective study utilized machine learning algorithms to evaluate the diagnostic performance of radiomics extracted from CT and MRI for identifying acute pancreatitis (AP), as defined by the revised Atlanta classification. The results demonstrated that MRI radiomics (specifically T2-weighted imaging) outperformed CT models, while a multi-modality approach combining both CECT and MRI achieved the highest diagnostic accuracy.
The researchers used mint Lesion to manually perform three-dimensional segmentation of the entire pancreatic parenchyma across CECT and multiple MRI sequences. This segmentation defined the volumes of interest from which 107 radiomics features—characterizing shape, intensity distribution, and texture—were extracted for analysis.
PET/CT imaging of differentiated and medullary thyroid carcinoma using the novel SSTR-targeting peptide [18F]SiTATE – first clinical experiences.
Kunte, S.C., Wenter, V., Toms, J. et al. (2025) Eur J Nucl Med Mol Imaging
DOI: 10.1007/s00259-024-06944-y
This study evaluates the feasibility of using the novel somatostatin receptor (SSTR)-directed radiotracer [18F]SiTATE for PET/CT imaging in patients with differentiated (DTC) and medullary thyroid carcinoma (MTC). The researchers found that [18F]SiTATE PET/CT effectively identifies metastatic lesions and correlates significantly with calcitonin tumor markers in MTC, offering a logistical alternative to 68Ga-based tracers for assessing peptide receptor radionuclide therapy (PRRT) eligibility. While PET results were compared using PERCIST 1.0, the study also noted that reporting could be standardized in the future using the SSTR-RADS 1.0 framework.
mint Lesion was employed to evaluate CT datasets by manually measuring target and non-target lesions. These assessments were conducted according to RECIST 1.1 guidelines to define the metastatic status at baseline and follow-up.
Bolus-Tracked Biphasic Contrast-Enhanced CT Imaging Following Microwave Liver Ablation Improves Ablation Zone Conspicuity and Semi-automatic Segmentation Quality.
Giansante, L., McDonagh, E., Basso, J. et al. (2025) Cardiovasc Intervent Radiol
DOI: 10.1007/s00270-024-03948-x
This clinical investigation demonstrates that bolus-tracked biphasic contrast-enhanced CT (CECT) significantly improves the conspicuity and semi-automatic segmentation quality of microwave liver ablation zones, particularly for colorectal cancer metastases. The results indicate that imaging quality declines by 3–4% for each minute that passes after ablation, making early post-procedural imaging critical for accurate assessment.
The study utilized mint Lesion's “interpolated VOI” tool to perform semi-automatic 3D segmentation of ablation zones, where an algorithm identifies object boundaries based on a user-defined rough extent. The software's performance was evaluated using a five-point Likert scale to measure the automated algorithm's quality and the necessity of manual intervention.
2024
Image quality of virtual monochromatic and material density iodine images for evaluation of head and neck neoplasms using deep learning-based CT image reconstruction – A retrospective observational study
Bürckenmeyer, F., Gräger, S., Mlynska et al. (2024) European Journal of Radiology
DOI: 10.1016/j.ejrad.2024.111806
Prospective close monitoring of the effect of vascular-targeted photodynamic therapy and high intensity focused ultrasound of localized prostate cancer by multiparametric magnetic resonance imaging
Solyanik, O., Chaloupka, M., Clevert, D. A. et. al. (2024) World Journal of Urology
DOI: 10.1007/s00345-024-05143-6
The prognostic relevance of pleural effusion in patients with COVID-19 - A German multicenter study
Bucher, A. M., Henzel, K., Meyer, H.J. et. al. (2024) Clinical Imaging
DOI: 10.1016/j.clinimag.2024.110303
Real-world response assessment of immune checkpoint inhibition: comparing iRECIST and RECIST 1.1 in melanoma and non-small cell lung cancer patients
Nelles, C., Gräf, M., Bernard, P. et. al. (2024) European Radiology
DOI: 10.1007/s00330-024-11060-4
Delta-radiomics features of ADC maps as early predictors of treatment response in lung cancer
Heidt, C.M, Bohn, J.R., Stollmayer, R. et. al. (2024) Insights into Imaging
DOI: 10.1186/s13244-024-01787-5
Predictive value of pre-infusion tumor growth rate for the occurrence and severity of CRS and ICANS in lymphoma under CAR T-cell therapy
Winkelmann, M., Blumenberg, V., Rejeski, K. et al. (2024) Annals of Hematology
DOI: 10.1007/s00277-023-05507-9
L-RNA aptamer-based CXCL12 inhibition combined with radiotherapy in newly-diagnosed glioblastoma: dose escalation of the phase I/II GLORIA trial
Giordano, F.A., Layer, J.P., Leonardelli, S., et al. (2024) nature communications
DOI: 10.1038/s41467-024-48416-9
Speeding Up and Improving Image Quality in Glioblastoma MRI Protocol by Deep Learning Image Reconstruction
Gohla, G., Hauser, T.K., Bombach, P. et al. (2024) Cancers
DOI: 10.3390/cancers16101827
Prospective study validating a multidimensional treatment decision score predicting the 24-month outcome in untreated patients with clinically isolated syndrome and early relapsing–remitting multiple sclerosis, the ProVal-MS study
Bayas, A., Mansmann, U., Ön, B. I. et al. (2024) Neurological Research and Practice
DOI: 10.1186/s42466-024-00310-x
Real-World Federated Learning in Radiology: Hurdles to overcome and Benefits to gain
Bujotzek, M.R., Akünal, Ü., Denner, S. et. al. (2024)
Comparison of Four Diagnostic Guidelines for Hepatocellular Carcinoma Using Gadoxetic Acid–enhanced Liver MRI
Yoon, J.H., Kim, Y.K., Kim, J.W. et. al. (2024) Radiology
DOI: 10.1148/radiol.233114
Imaging differentiation of solid pseudopapillary neoplasms and neuroendocrine neoplasms of the pancreas
Khristenko, E., Gaida, M.M., Tjaden, Ch. et al. (2024) European Journal of Radiology Open
DOI: 10.1016/j.ejro.2024.100576
Glioblastoma Multiforme Tumor Volume and Persistence of Chimeric Antigen Receptor T Cells Following Neurosurgical Debulking
Veerappan, D., Thomas, R. (2024) Neurology Journal
DOI: 10.1212/WNL.0000000000205643
Robustness of radiomic features in healthy abdominal parenchyma of patients with repeated examinations on dual-layer dual-energy CT
Schöneck, M., Lennartz, M., Zopfs, D. et. al. (2024) European Journal of Radiology
DOI: org/10.1016/j.ejrad.2024.111447
Radiolabeled Somatostatin Receptor Antagonist Versus Agonist for Peptide Receptor Radionuclide Therapy in Patients with Therapy-Resistant Meningioma: PROMENADE Phase 0 Study
Eigler, C., McDougall, L., Bauman, A. et al. (2024) Journal of Nuclear Medicine
DOI: 10.2967/jnumed.123.266817
Tumor Response Evaluation Using iRECIST: Feasibility and Reliability of Manual Versus Software-Assisted Assessments
Ristow, I., Well, L., Wiese, N. J. et al. (2024) Cancers
DOI: 10.3390/cancers16050993
DiffErentiable TEmporal ContrasT (DETECT) Loss for Liver Cancer Screening in 4D Dynamic Contrast-Enhanced MRI
Monnin, K., Jeltsch, P., Fernandes-Mendes, L. et al. (2024) MIDL
Applicability of the CT Radiomics of Skeletal Muscle and Machine Learning for the Detection of Sarcopenia and Prognostic Assessment of Disease Progression in Patients with Gastric and Esophageal Tumors
Vogele, D., Mueller, T., Wolf, D. et al. (2024) Diagnostics
DOI: 10.3390/diagnostics14020198
2023
Association of Tumor Volumetry with Postoperative Outcomes for Cervical Paraganglioma
Hoffmann-Wieker, C.M., Rebelo, A., Moll, M., et.al (2023) Diagnostics
DOI: 10.3390/diagnostics13040744
Integration of clinical parameters and CT-based radiomics improves machine learning assisted subtyping of primary hyperaldosteronism
Mansour, N., Mittermeier, A., Walter, R. et al. (2023) Frontiers in Endocrinology
DOI: 10.3389/fendo.2023.1244342
Pericardial Effusion Predicts Clinical Outcomes in Patients with COVID-19: A Nationwide Multicenter Study
Bucher, A. M., Henzel, K., Meyer, H. J. et al. (2023) Academic Radiology
DOI: 10.1016/j.acra.2023.12.003
Patterns of radiological response to tebentafusp in patients with metastatic uveal melanoma
Roshardt Prieto, N. M., Turk,o P., Zellweger, C. et al. (2023) Melanoma Research
DOI: 10.1097/CMR.0000000000000952
Radiomics and Clinicopathological Characteristics for Predicting Lymph Node Metastasis in Testicular Cancer
Lisson, C. S., Manoj, S., Wolf, D. et al. (2023) Cancers
DOI: 10.3390/cancers15235630
Clinician and Patient Preference of Multimedia-Enhanced Radiology Reporting for Primary Tumour Staging: an Exploratory Study
Shur, J., Hainsworth, E., Kafaei, L. et al. (2023) SN Comprehensive Clinical Medicine
DOI. 10.1007/s42399-023-01618-6
Selective Internal Radiotherapy (SIRT) and Chemosaturation Percutaneous Hepatic Perfusion (CS-PHP) for Metastasized Uveal Melanoma: A Retrospective Comparative Study
Kolb, M., Forschner, A., Artzner, C. et al. (2023) Cancers
DOI: 10.3390/cancers15204942
Radiomic Assessment of Radiation-Induced Alterations of Skeletal Muscle Composition in Head and Neck Squamous Cell Carcinoma within the Currently Clinically Defined Optimal Time Window for Salvage Surgery—A Pilot Study
Santer, M., Riechelmann, H., Hofauer, B. et al. (2023) Cancers
DOI: 10.3390/cancers15184650
Discrepant Assessments of Progressive Disease in Clinical Trials between Routine Clinical Reads and Formal RECIST 1.1 Interpretations
Siegel, M. J., Ippolito, J. E., Wahl, R. L. et al. (2023) Radiology: Imaging Cancer
DOI: 10.1148/rycan.230001
Diffusion-Weighted MRI for Treatment Response Assessment in Osteoblastic Metastases—A Repeatability Study.
Eveslage, M., Rassek, P., Riegel, A. et al. (2023) Cancers
DOI: 10.3390/cancers15153757
Pretherapy Ferumoxytol-enhanced MRI to Predict Response to Liposomal Irinotecan in Metastatic Breast Cancer
Ravi, H., Arias-Lorza, A. M., Costello, J. R. et al. (2023) Radiology: Imaging Cancer
DOI: 10.1148/rycan.220022
Safety, tolerability, and effectiveness of the sodium-glucose cotransporter 2 inhibitor (SGLT2i) dapagliflozin in combination with standard chemotherapy for patients with advanced, inoperable pancreatic adenocarcinoma: a phase 1b observational study
Park, L.K., Lim, KH., Volkman, J. et al. (2023) Cancer & Metabolism
DOI: 10.1186/s40170-023-00306-2
Whole-body diffusion magnetic resonance imaging with simultaneous multi-slice excitation in children and adolescents
Krueger, PC., Krämer, M., Benkert, T. et al. (2023) Pediatric Radiology
DOI: 10.1007/s00247-023-05622-9
CT Radiomics and Clinical Feature Model to Predict Lymph Node Metastases in Early-Stage Testicular Cancer
Lisson, C. S., Manoj, S., Wolf, D. et al. (2023) Onco
DOI: 10.3390/onco3020006
Downsizing of rectal cancer following neoadjuvant radiotherapy (5 × 5 Gy) and long interval surgery evaluated using MRI semiautomated volumetric measurements, a retrospective study
Albrecht, H .C., Wagner, S., Sandbrink, C. et al. (2023) Frontiers in Surgery., Sec. Visceral Surgery
DOI: 10.3389/fsurg.2023.1106177
A VISION Substudy of Reader Agreement on 68Ga-PSMA-11 PET/CT Scan Interpretation to Determine Patient Eligibility for 177Lu-PSMA-617 Radioligand Therapy
Kuo, P.H., Yoo, D. C., Avery, R. et al. (2023) Journal of Nuclear Medicine
DOI: 10.2967/jnumed.122.265077
Added value of chest CT in a machine learning-based prediction model to rule out COVID-19 before inpatient admission: A retrospective university network study
Krämer, M., Ingwersen, M., Teichgräber, U. et al. (2023) European Journal of Radiology
DOI: 10.1016/j.ejrad.2023.110827
2022
CODEX Meets RACOON - A Concept for Collaborative Documentation of Clinical and Radiological COVID-19 Data
Schmidt, M., Gebauer, S., Bartholmes, A. et al. (2022) German Medical Data Sciences 2022 - Future Medicine
DOI: 10.3233/SHTI220804
Translational analysis and final efficacy of the AVETUX trial – Avelumab, cetuximab and FOLFOX in metastatic colorectal cancer
Tintelnot, J., Ristow, I., Sauer, M. et al. (2022) Frontiers in Oncology
DOI: 10.3389/fonc.2022.993611
Prognostic value of the International Metabolic Prognostic Index for lymphoma patients receiving chimeric antigen receptor T-cell therapy
Winkelmann, M., Blumenberg, V., Rejeski, K. et al. (2022) European Journal of Nuclear Medicine and Molecular Imaging
DOI: 10.1007/s00259-022-06075-2
Three-Dimensional Software- and MR-Imaging-Based Muscle Volumetry Reveals Overestimation of Supraspinatus Muscle Atrophy Using Occupation Ratios in Full-Thickness Tendon Tears
Goller, S.S., Erber, B., Fink, N. et al. (2022) Healthcare
DOI: 10.3390/healthcare10101899
Therapeutic Outcome of MR‐Guided High‐Intensity Focused Ultrasound (MR‐HIFU) in Solitary versus Multiple Uterine Fibroids
Erber, B., Schwarze, V., Strobl, F. et al. (2022) Healthcare
DOI: 10.3390/healthcare10081471
Targeted parallel DNA sequencing detects circulating tumor-associated variants of the mitochondrial and nuclear genomes in patients with neuroblastoma
Riehl, L., Mulaw, M., Kneer, K., Beer, M. et al. (2022) Cancer Reports
DOI: 10.1002/cnr2.1687
A novel free-breathing abdominal RAVE T2/T1 hybrid MRI sequence in patients with cystic fibrosis: Preliminary results
Glutig, K., Krüger, P.C., Oberreuther, T. et al. (2022) European Journal of Radiology
DOI: 10.1016/j.ejrad.2022.110454
Total Tumor Volume on 18F-PSMA-1007PET as Additional Imaging Biomarker in mCRPC Patients Undergoing PSMA-Targeted Alpha Therapy with 225Ac-PSMA-I&T
Unterrainer, L.M., Beyer, L., Zacherl, M.J. et al. (2022) Biomedicines
DOI: 10.3390/biomedicines10050946
iRECIST based versus non standardized free text reporting of CT scans for monitoring metastatic renal cell carcinoma: a retrospective comparison
Schomburg, L., Malouhi, A., Grimm, M.-O. et al. (2022) Journal of Cancer Research and Clinical Oncology
DOI: 10.1007/s00432-022-03997-0
Longitudinal CT Imaging to Explore the Predictive Power of 3D Radiomic Tumour Heterogeneity in Precise Imaging of Mantle Cell Lymphoma (MCL)
Lisson, C.S., Lisson, C.G., Achilles, S., et al. (2022) Cancers
DOI: 10.3390/cancers14020393
Semi-Automatic MRI Feature Assessment in Small- and Medium-Volume Benign Prostatic Hyperplasia after Prostatic Artery Embolization
Schmidt, V.F., Schirren, M., Heimer, M.M. et al. (2022) Diagnostics
DOI: 10.3390/diagnostics12030585
Volumetric endpoints in diffuse intrinsic pontine glioma: comparison to cross-sectional measures and outcome correlations in the International DIPG/DMG Registry
Lazow, M. A., Nievelstein, M. T., Lane, A. et al. (2022) Neuro-Oncology
DOI: 10.1093/neuonc/noac037
2021
Gegenwärtige Entwicklungen in der Healthcare-Informationstechnologie
Christlein, D., Kast, J., Baumhauer, M. (2021) Die Radiologie
DOI: 10.1007/s00117-021-00924-1
MRI Radiomics Features Correlate with Histologic Tumor Necrosis Following Neoadjuvant Radiation Therapy in Extremity Soft Tissue Sarcoma
Seldon, C., Grosso, J., Subhawong, T. et al. (2021) American Journal of Clinical Oncology
DOI: 10.1097/COC.0000000000000862
A Machine learning model trained on dual-energy CT radiomics significantly improves immunotherapy response prediction for patients with stage IV melanoma
Brendlin, A.S., Peisen, F., Almansour, H. et al. (2021) Journal for ImmunoTherapy of Cancer
DOI: 10.1136/jitc-2021-003261
Supervised learning based on tumor imaging and biopsy transcriptomics predicts response of hepatocellular carcinoma to transarterial chemoembolization
Boldanova, T., Geoffrey Fucile, G., Vosshenrich, J. et al. (2021) Cell Reports Medicine
DOI: 10.1016/j.xcrm.2021.100444
Combined transarterial embolization, and percutaneous sclerotherapy as treatment for refractory and non resectable aneurysmal bone cysts
Masthoff, M., Gerwing, M., Schneider, K. N. et al. (2021) Journal of Vascular and Interventional Radiology
DOI: 10.1016/j.jvir.2021.07.008
Comparison of CT Texture Analysis Software Platforms in Renal Cell Carcinoma: Reproducibility of Numerical Values and Association With Histologic Subtype Across Platforms
Dreyfuss, L. D., Jason Abel, E., Nystrom, J. et al. (2021) American Journal of Roentgenology
DOI: 10.2214/AJR.20.22823
Early Tumor Size Reduction of at least 10% at the First Follow-Up Computed Tomography Can Predict Survival in the Setting of Advanced Melanoma and Immunotherapy
Almansour, H., Afat, S., Serna-Higuita, L. M. et al. (2021) Academic Radiology
DOI: 10.1016/j.acra.2021.04.015
Superficial fibromatosis: MRI radiomics and T2 mapping correlate with treatment response
Ramachandran, A., Fox, T., Wolfson, A., Banks, J. et al. (2021) Magnetic Resonance Imaging
DOI: 10.1016/j.mri.2021.06.003
A reporting and analysis framework for structured evaluation of COVID-19 clinical and imaging data
Salg, G.A., Ganten, MK., Bucher, A.M. et al. (2021) npj Digital Medicine
DOI: 10.1038/s41746-021-00439-y
Radiological evaluation of pancreatic cancer: What is the significance of arterial encasement >180° after neoadjuvant treatment?
Mayer, P., Giannakis, A., Klauß, M. et al. (2021) European Journal of Radiology
DOI: 10.1016/j.ejrad.2021.109603
Texture analysis of iodine maps and conventional images for k-nearest neighbor classification of benign and metastatic lung nodules
Lennartz, S., Mager, A., Große Hokamp, N. et al. (2021) Cancer Imaging
DOI: 10.1186/s40644-020-00374-3
18F-FDG-PET/CT in Patients with Advanced, Radioiodine Refractory Thyroid Cancer Treated with Lenvatinib
Ahmaddy, F., Burgard, C., Beyer, L. et al. (2021) Cancers
DOI: 10.3390/cancers13020317
2020
18F-PSMA-1007 PET/CT for response assessment in patients with metastatic renal cell carcinoma undergoing tyrosine kinase or checkpoint inhibitor therapy: preliminary results
Mittlmeier, L.M., Unterrainer, M., Rodler, S. et al. (2020) European Journal of Nuclear Medicine and Molecular Imaging
DOI: 10.1007/s00259-020-05165-3
Response prediction of hepatocellular carcinoma undergoing transcatheter arterial chemoembolization: unlocking the potential of CT texture analysis through nested decision tree models
Vosshenrich, J., Zech, C.J., Heye, T. et al. (2020) European Radiology
DOI: 10.1007/s00330-020-07511-3
Validation of Prognostic Radiomic Features From Resectable Pancreatic Ductal Adenocarcinoma in Patients With Advanced Disease Undergoing Chemotherapy
Salinas-Miranda, E., Khalvati, F., Namdar, K. et al. (2020) Sage Journals
DOI: 10.1177/0846537120968782
A phase I/II study of ribociclib following radiation therapy in children with newly diagnosed diffuse intrinsic pontine glioma (DIPG)
DeWire, M., Fuller, C., Hummel, T.R. et al. (2020) Journal of Neuro-Oncology
DOI: 10.1007/s11060-020-03641-2
Intraindividual Consistency of Iodine Concentration in Dual-Energy Computed Tomography of the Chest and Abdomen
Zopfs, D., Graffe, J., Reimer, R.P. et al. (2020) Investigative Radiology
DOI: 10.1097/RLI.0000000000000724
Nivolumab plus ipilimumab for soft tissue sarcoma: a single institution retrospective review
Zhou, M., Nam Bui, N., Bolleddu, S. et al. (2020) Future Medicine. Immunotherapy
DOI: 10.2217/imt-2020-0155
Quantitative distribution of iodinated contrast media in body computed tomography: data from a large reference cohort
Zopfs, D., Graffe, J., Reimer, R.P. et al. (2020) European Radiology
DOI: 10.1007/s00330-020-07298-3
CT texture analysis compared to Positron Emission Tomography (PET) and mutational status in resected melanoma metastases
Olthof, S.-C., Krumm, P., Weichold, O. et al. (2020) European Journal of Radiology
DOI: 10.1016/j.ejrad.2020.109242
Response rate and safety in patients with hepatocellular carcinoma treated with transarterial chemoembolization using 40-µm doxorubicin-eluting microspheres
Albrecht, K.C., Aschenbach, R., Diamantis, I. et al. (2020) Journal of Cancer Research and Clinical Oncology
DOI: 10.1007/s00432-020-03370-z
Tumor Response Assessment in Diffuse Intrinsic Pontine Glioma: Comparison of Semiautomated Volumetric, Semiautomated Linear, and Manual Linear Tumor Measurement Strategies
Gilligan, L.A., DeWire-Schottmiller, M.D., Fouladi, M. (2020) American Journal of Neuroradiology
DOI: 10.3174/ajnr.A6555
A globally available COVID-19 - Template for clinical imaging studies
Salg, A. G., Ganten, M.-K., Baumhauer, M. et al. (2020) medRxiv
DOI: 10.1101/2020.04.02.20048793
2019
Response evaluation for immunotherapy through semi-automatic software based on RECIST 1.1, irRC, and iRECIST criteria: comparison with subjective assessment
Lai, Y.-C., Chan, W.-C., Chen, C.-B. et al. (2019) Acta Radiologica
DOI: 10.1177/0284185119887588
Early Prediction of Treatment Response of Neuroendocrine Hepatic Metastases after Peptide Receptor Radionuclide Therapy with 90Y-DOTATOC Using Diffusion Weighted and Dynamic Contrast-Enhanced MRI
Weikert, T., Maas, O. C., Haas, T. et al. (2019) Contrast Media & Molecular Imaging
DOI: 10.1155/2019/1517208
Combined Qualitative and Quantitative Assessment of Low-Attenuation Renal Lesions Improves Identification of Renal Malignancy on Noncontrast Computed Tomograph
Picard, M., Shah, N., Flemming, B. et al. (2019) Journal of Computer Assisted Tomography
DOI: 10.1097/RCT.0000000000000930
The positivity rate of 68Gallium-PSMA-11 ligand PET/CT depends on the serum PSA-value in patients with biochemical recurrence of prostate cancer
Hoffmann, M. A., Buchholz, H-G., Wieler, H.J. et al. (2019) Oncotarget
DOI: 10.18632/oncotarget.27239
Strukturierte Befundung und standardisiertes Therapiemonitoring
Persigehl, T., Gebauer, F., Bruns, C. et al. (2019) Die Onkologie
DOI: 10.1007/s00761-019-00685-6
Baseline clinical and imaging predictors of treatment response and overall survival of patients with metastatic melanoma undergoing immunotherapy
Schraag, A., Klumpp, B., Afat, S. et al. (2019) European Journal of Radiology
DOI: 10.1016/j.ejrad.2019.108688
2018
Radiologic and Genomic Evolution of Individual Metastases during HER2 Blockade in Colorectal Cancer
Siravegna, G., Lazzari, L., Crisafulli, G. et al. (2018) Cancer Cell
DOI: 10.1016/j.ccell.2018.06.004
Diagnostic value of MRI-based 3D texture analysis for tissue characterisation and discrimination of low-grade chondrosarcoma from enchondroma: a pilot study
Lisson, C.S., Lisson, C.G., Flosdorf, K. et al. (2018) European Radiology
DOI: 10.1007/s00330-017-5014-6. Epub 2017 Sep 7
Safety, Biodistribution, and Radiation Dosimetry of 68Ga-OPS202 in Patients with Gastroenteropancreatic Neuroendocrine Tumors: A Prospective Phase I Imaging Study
Nicholas, G. P., Beykan, S., Bouterfa, H. et al. (2018) Journal of Nuclear Medicine
DOI: 10.2967/jnumed.117.199737
Sensitivity Comparison of 68Ga-OPS202 and 68Ga-DOTATOC PET/CT in Patients with Gastroenteropancreatic Neuroendocrine Tumors: A Prospective Phase II Imaging Study
Nicholas, G. P., Schreiter, N., Kaul, F. et al. (2018) Journal of Nuclear Medicine
DOI: 10.2967/jnumed.117.199760
Assessment of Therapy Response to Transarterial Radioembolization for Liver Metastases by Means of Post-treatment MRI-Based Texture Analysis
Reimer, R.P., Reimer, P., Mahnken, A.H. (2018) CardioVascular and Interventional Radiology
DOI: 10.1007/s00270-018-2004-2
Value of computed tomography texture analysis for prediction of perioperative complications during laparoscopic partial nephrectomy in patients with renal cell carcinoma
Bier, G., Bier, S., Bongers, M.N., Othman, A. et al. (2018) PLOS ONE
DOI: 10.1371/journal.pone.0195270
18F-FDOPA PET/MRI for monitoring early response to bevacizumab in children with recurrent brain tumors
Gauvain, K., Ponisio, M. R., Barone, A. et al. (2018) Neuro-Oncology Practice
DOI: 10.1093/nop/npx008
2017
Radiologische Responsebeurteilung moderner Immuntherapien mithilfe von iRECIST
Persigehl, T., Poeppel T.D., Sedlaczek, O. (2017) Die Radiologie
DOI: 10.1007/s00117-017-0289-9
Response Evaluation of Malignant Liver Lesions After TACE/ SIRT: Comparison of Manual and Semi-Automatic Measurement of Different Response Criteria in Multislice CT
Höink, A.J., Schülke, C., Koch, R. et al. (2017) RöFo
DOI: 10.1055/s-0043-116220
Circulating Tumor DNA Quantitation for Early Response Assessment of Immune Checkpoint Inhibitors for Lung Cancer
Merriott, D.J., Chaudhuri, A.A., Jin, M. et al. (2017) International Journal of Radiation Oncology Biology Physics
DOI: 10.1016/j.ijrobp.2017.06.061
Successful Yttrium-90 Microsphere Radioembolization for Hepatic Metastases of Prostate Cancer
Bunck, A.C., Pinto dos Santos, D., Chang, D-H. et al. (2017) Case Reports in Oncology
DOI: 10.1159/000478004
Tumor response assessment: comparison between unstructured free text reporting in routine clinical workflow and computer-aided evaluation based on RECIST 1.1 criteria
Goebel, J., Hoischen, J., Gramsch, C. et al. (2017) Journal of Cancer Research and Clinical Oncology
DOI: 10.1007/s00432-017-2488-1
2016
Tumorverlaufsbildgebung in der täglichen Praxis: Vergleich der Befundung mittels Freitext und mittels RECIST 1.1 Kriterien
Naßenstein, K., Göbel, J., Hoischen, J. et al. (2016) RöFo - Fortschritte auf dem Gebiet der Röntgenstrahlen und der bildgebenden Verfahren
DOI 10.1055/s-0036-1581767
Moderne Diagnostik und standardisiertes Therapie-Monitoring beim malignen Melanom. Strukturierte Befundung als Grundlage der personalisierten Medizin
Persigehl, T., Pöppel, T. D. (2016) Forum
DOI: 10.1007/s12312-016-0131-8
Dual-targeted therapy with trastuzumab and lapatinib intreatment-refractory, KRAS codon 12/13 wild-type, HER2-positive metastatic colorectal cancer (HERACLES): a proof-of-concept, multicentre, open-label, phase 2 trial.
Sartore-Bianchi, A., Trusolino, L., Martino, C., et al. (2016) The Lancet Oncology
DOI: 10.1016/S1470-2045(16)30463-6
2014
Radiological Evaluation of the Therapeutic Response of Malignant Diseases: Status Quo, Innovative Developments and Requirements for Radiology
Höink, A. J., Heindel, W., Buerke, B. (2014) RöFo
DOI: 10.1055/s-0034-1366741
2013
Early Treatment Response Evaluation after Yttrium-90 Radioembolization of Liver Malignancy with CT Perfusion
Reiner, C.S., Morsbach, F., Sah, B.-R. et al. (2013) Journal of Vascular and Interventional Radiology
DOI: 10.1016/j.jvir.2014.01.025
Colorectal cancer: current imaging methods and future perspectives for the diagnosis, staging and therapeutic response evaluation
Kekelidze, M., D'Errico L., Pansini M., et al. (2013) World Journal of Gastroenterology
DOI: 10.3748/wjg.v19.i46.8502
Bildgebende Beurteilung des Therapieansprechens unter Chemotherapie
Layer, G., Stahl T., Hoffend, J. (2013) Radiologie up2date 2013
DOI: 10.1055/s-0033-1344352
Therapy response assessment in metastatic melanoma patients treated with a BRAF inhibitor: adapted Choi criteria can reflect early therapy response better than does RECIST
Uhrig, M., Hassel, J.C., Schlemmer, H.-R., et al. (2013) Academic radiology
DOI: 10.1016/j.acra.2012.09.029