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Comparison of iRECIST and RECIST 1.1 for Evaluating Immunotherapy in Melanoma and Non-Small Cell Lung Cancer

In a retrospective study conducted at the University Hospital Cologne, the radiological criteria iRECIST and RECIST 1.1 were compared for assessing treatment response in melanoma and NSCLC patients receiving immune checkpoint inhibitors.

The results indicate that iRECIST is better suited for capturing atypical treatment responses to immunotherapies, especially in patients experiencing pseudoprogression. iRECIST could thus contribute to a more accurate evaluation of treatment response and improved immunotherapy outcomes.

Read more about the study here.

Screenshot of the mint Lesion interface showing RANO 2.0 configuration, tumor burden calculations, and structured neuro-oncology assessment tools.
mint Lesion fully supports RANO 2.0 implementation with configurable parameters, automated tumor burden calculations, and structured workflows for neuro-oncology clinical trials.
Implementing RANO 2.0 for Neuro-Oncology Clinical Trials in mint Lesion

Tumor response assessment in neuro-oncology clinical trials requires careful attention to measurement protocols and confirmation scan requirements. To…

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Image of a patient getting an MRI scan, signifying how RACOON projects in Germany show how imaging, structured reporting, and AI jointly advance clinical research.
Overview of major RACOON projects in radiology and clinical research.
RACOON – Imaging, Data & Collaboration for Better Decisions

Modern radiology faces a central question: how can imaging and clinical data be combined in a way that leads to more precise diagnoses,…

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Interview with Prof. Timm Denecke about the RACOON-MARDER project and AI-powered early detection of liver cancer using MRI
An in-depth interview with Prof. Timm Denecke about the RACOON-MARDER project
Rethinking Early Detection: How RACOON-MARDER Aims to Spot Liver Cancer Sooner

Hepatocellular carcinoma (HCC) is often diagnosed too late, limiting treatment options and survival. The RACOON-MARDER project aims to change that. By…

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